Isiolo County has three constituencies; Laisamis, Isiolo North, and Isiolo South. Governor Abdi Hassan Guyo heads the county.
Below is a list of MPs in Isiolo County.
List Of MPs In Isiolo County
| Constituency | MP | Party |
| Laisamis | Joseph Lekuton | UDM |
| Isiolo North | Joseph Samal Lomwa | Jubilee |
| Isiolo South | Bidu Mohamed Tubi | Jubilee |