Homa Bay County has eight constituencies: Kasipul, Kabondo Kasipul, Karachuonyo, Rangwe, Homa Bay Town, Ndhiwa, Suba North, and Suba South. Governor Gladys Wanga heads the county.
Below is a list of MPs in Homa Bay County.
List of MPs in Homa Bay County
| Constituency | MP | Party |
| Kasipul | Charles Ong’ondo Were | ODM |
| Kabondo Kasipul | Eve Akinyi Obara | ODM |
| Karachuonyo | Andrew Adipo Okuome | ODM |
| Rangwe | Lilian Achieng Gogo | ODM |
| Homa Bay Town | George Peter Opondo Kaluma | ODM |
| Ndhiwa | Martins Peters Owino | ODM |
| Suba North | Millie Odhiambo | ODM |
| Suba South | Caroli Omondi | ODM |